Completed Research

The LITE Study

A Randomized Controlled Trial of Light Therapy for Cancer-related Fatigue

The LITE study is randomized controlled trial of light therapy for the treatment of cancer-related fatigue (CRF) in 124 post-treatment cancer patients. CRF is one of the most common and distressing symptoms that comes with a cancer diagnosis. It is a feeling of extreme exhaustion and lack of energy and is not relieved by rest or sleep. This type of fatigue often appears before a cancer diagnosis, worsens during treatment, and can last for months or even years after treatments have ended in up to 35% of patients. The LITE Study is being conducted at the University of Calgary and is funded by the Canadian Cancer Society Research Institute

Please visit http://www.thelitestudy.ca

Investigators

Primary Investigator:

Tavis Campbell, PhD (University of Calgary)

Co-Investigators:

Jillian Johnson, MSc (University of Calgary),

Linda Carlson, PhD (University of Calgary),

Sheila N Garland, PhD (Memorial University of Newfoundland),

Josee Savard, PhD (Laval University),

Steve Simpson, MD, FRCPC (University of Calgary),

Sonia Ancoli-Israel, PhD (University of California, San Diego)

Representative Publications

Johnson, J. A., Garland, S. N., Carlson, L. E., Savard, J., Simpson, J.S. A., Ancoli-Israel, S. Campbell, T. (2016). The LITE study: Rational and protocol for a randomized controlled trial of light therapy for cancer-related fatigue in cancer survivors. Contemporary Clinical Trials, 49, 166-173. PMID: 27394380

I-CAN SLEEP

A research program for patients with Insomnia and CANcer

An objective comparison of cognitive behavioral therapy and mindfulness-based cancer recovery for the treatment of insomnia in cancer survivors using wrist actigraphy: a randomized noninferiority trial

The I-CAN SLEEP study investigated the effect of two psychosocial programs on insomnia symptoms in a heterogeneous sample of 111 cancer survivors. Mindfulness-Based Cancer Recovery (MBCR) teaches stress reduction through meditation and yoga and was compared to Cognitive-Behavior Therapy for Insomnia (CBT-I), to determine whether it produced similar effects with the added benefit of reduced stress and mood disturbance. The I-CAN SLEEP study was conducted at the University of Calgary and was funded by the Canadian Cancer Society Research Institute.

Investigators

Primary Investigator:

Tavis Campbell, PhD

Co-Investigators:

Sheila Garland, PhD,

Linda Carlson, PhD,

Mike Antle, PhD,

Charles Samuels, MD

Representative Publications

Garland, S. N., Rouleau, C. R., Campbell, T., Samuels, C., & Carlson, L. E. (2015). The Comparative Impact of Mindfulness-Based Cancer Recovery (MBCR) and Cognitive Behavior Therapy for Insomnia (CBT-I) on Sleep and Mindfulness in Cancer Patients. Explore: The Journal of Science and Healing, 11(6), 445-454. PMID: 26386748

Garland, S. N., Carlson, L. E., Stephens, A., Antle, M., Samuels, C., & Campbell, T. (2014). Mindfulness-based stress reduction compared to cognitive behavioral therapy for the treatment of insomnia comorbid with cancer: a randomized, partially blinded, non-inferiority trial. Journal of Clinical Oncology, 32 (5), 449-57. PMID: 24395850

Garland, S. N., Campbell, T. S., Samuels, C. & Carlson, L. E. (2013). Associations between dispositional mindfulness, insomnia, sleep quality and dysfunctional sleep beliefs in post-treatment cancer patients. Personality and Individual Differences, 55(3), 306-311.

Garland, S. N., Carlson, L. E., Antle, M., Samuels, C., & Campbell, T. (2011). I-CAN SLEEP: Rationale and design of a non-inferiority RCT of mindfulness-based stress reduction (MBSR) and cognitive behavioral therapy (CBT) for the treatment of insomnia in cancer survivors. Contemporary Clinical Trials, 32(5), 747-754. PMID: 21658476.